I have a friend who has a DVD drive that runs slowly without DMA enabled on it (obviously), but with DMA enabled, it apparently extracts incorrect data. Programs run from it (like an installer) usually fail, and DVD playback is glitchy. I blame it on being an off-brand DVD (Afreey?) and the VIA chipset on his motherboard. I haven't tried putting it on a PCI IDE controller yet.
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Bitt Faulk