The solution to the silkscreen problem with rubberized buttons is to not use silkscreen. Many of the one-for-all remotes embed the markings directly into the button, so as it wears down, the markings remain. Neither of my OFA remotes has ever had the button markings disappear (not that I'd care, because I can touch type on them.)

The layout of the Harmony One looks more sane than the 880, but it doesn't have enough hard buttons for my liking. The touchscreen should always be a last resort, IMHO, for really complicated stuff.

My ideal remote would probably have the "activity" behavior of the Harmony remotes, several more hard buttons than the Harmony One has, a regular info screen in lieu of the touchscreen, and rubberized buttons. The likelihood of something like that coming along is low, but for what they charge for remotes, I'm going to wait for it.