This is a nice thread we have going, actually. My five years:

2006 - Moved to new job at a law firm in DC, as IT admin.
2007 (June-July) - Got married, followed by a dream honeymoon in Italy. Moved into my first home with my wife, living together for the first time. Virtually no problems with that and it's been wonderful.
2007 (October) - laid off from job at the law firm, went into business for myself doing in-home and small business tech support, and loving being my own boss.
2009 (May) - Lost my father to a five year battle with cancer.
2009 (November) - helped my mom move out of the family home of 25 years but into a place that's perfect for her
2010 - looking forward to a better year.
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Matt