Originally Posted By: Taym
Have you guys had some good experience with good external enclosures (and Windows Server)?


Can't really help: I haven't run Windows Server since Windows 2012 was a thing, and I'm using plain-ol' NAS (SMB, mostly) for most things these days.

Originally Posted By: Taym
Thunderbolt 3 seems today the best performing interface, if I wanted Windows to see the external drives as JBOD and create its RAID array.


My concern here is whether your Windows PC supports Thunderbolt 3. My Surface Book 3, for instance, doesn't (it's a deliberate security-related thing).

Originally Posted By: Taym
Would it be a solid reliable solution? Meaning, would it be reasonable to assume that Windows could manage such drives as reliably as it would internal disks?


Yes, I wouldn't have any concerns doing this. You might need to tweak some settings so that Windows doesn't see the disks as removable if you want more speed.
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-- roger