The classic method, practiced since forever, is to have a central ‘amplifier’/AVR unit, then run analog speakers cables’ to wherever you want sound to come out. Downside is gauge and number of wires running from the central AVR out to the speaker locations, and difficulty of relocating speakers later. Or adding more speakers in other rooms, especially beyond the typical ‘second zone’, etc.

Future forward approach is to keep the signal digital and place compact amplifier and speaker together wherever you want sound. Digital can also be wireless, and the amplifier can be integrated into the speaker cabinet.

The only wire at each speaker is the AC power cord to nearby outlet. And sometimes that can be integrated into the wall cavity along with the speaker itself.

If not using wireless for the sound signals CATx cable can be used. Easy to route and wire distance doesn’t matter much.

AirPlay, Sonos and others offer wireless and CATx alternatives to the ‘speakers only where I can run speaker wires’ limitations.