It doesn't make any sense to me that I'd have to manually configure specs or "tweak" to get the RAM running at 533MHz, its advertised speed.

I didn't buy this RAM to overclock or otherwise speed-bump any of my settings. I just want to run at rated speeds on everything. CPU running at default settings to get my the advertised 2.66GHz speed. And I assumed, pop in the memory, have the system read its settings, and it should also run at advertised/labeled speeds.

Why label the memory 5-5-5-15 2.0v and then set up the SPD with different numbers?

EPP ("SPD") is enabled by default on my motherboard.